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1000 MCQ on Biotechnology

 1: History of plant tissue culture and genetic engineering; scope and 

importance in crop improvement  

1 …………………… known as father of plant tissue culture. 

 (a) Haberlandt (b) Robbins 

 (c) White (d) Miller 

2 The hormone 'Kinetin'  was discovered by  

 (a) Melchers et al. (b) Miller et al.  

 (c) Power  (d) Braun 

3 The meristem culture technique is developed by   

 (a) Morel and Martin (b) Murashige 

 (c) Webber (d) Redenbergh 

 

4 Karl Ereky basically which of the following 

 (a) Hungarian Engineering 

 

(b) Italian scientist 

 (c) Hungarian Biochemist (d) Hungarian Biotechnologist 

5 Biotechnology is the _________use of biological agent 

 (a) Open     (b) Controlled 

 (c) Accessible   (d) Limited 

6 The term totipotency was coined by   

 (a) Morgan (b) Volchting 

 (c) Tulecke (d) White 

7 Van Overbeek (1941) was used which natural plant product for 

growth of immature embryo 

 (a) Coconut milk (b) Liquid endosperm 

 (c) Plant endosperm (d) Both A and B 

8 First haploid plants were produced from pollen grain of datura by 

 (a) Power et al  Guha and Maheshwari 

 (c) Guha  Maheshwari 

9 The first embryo culture were developed by …..  

 (a) Tracul (b) White 

 (c) Henning (d) Robbin 

10 The term somaclonal variation was introduced by 

 (a) Takebe (b) Larkin  

 

 (c) Larkin and Scowcroft (d) Scowcroft 

11 Who is regarded as father of Indian embryology 

 (a) Guha (b) Maheshawari 

 (c) Guha and Maheshwari (d) Bourgin and Nitsch 

12 Who were first time used commercial enzyme for protoplast isolation 

 (a) Takebe et al 

 

(b) Cocking et al 

 

 (c) White (d) Both A and B 

13 In which of the year Maxam-Gilbert gave technology for DNA 

sequencing? 

 (a) 1977 (b) 1987 

 (c) 1967 (d) 1957 

14 Biolistic gene transformation method for plant transformation was 

developed by 

 (a) Borton  (b) Klien 

 (c) Williams (d) Smith 

15 Biolistic gene transformation method was developed in year…….. 

 (a) 1987 (b) 1990 

 (c) 1995 (d) 2000 

16 In which year International Rice Genome Sequencing Project was 

completed? 

 (a) 2000 (b) 2005 

 (c) 2010 (d) 2015  

17 The term biotechnology was coined by   

 (a) Kary Mullis  (b) Volchting 

 (c) Webber (d) Karl Ereky 

18 Bt gene isolated by 

 (a) Barton et al (b) Fodor 

 (c) Williams (d) Powell 

19 Biotechnology is the _________use of biological agent 

 (a) Open     (b) Controlled 

 (c) Accessible   (d) Limited 

20 The chemical used to protect cell or tissue against freezing injury is 

 (a) NH4 (b) Methyl sulphonate 

 

 (c) Dimethyle sulphonate (d) DMSO 

21 Non coding sequence of gene is called   

 (a) Recon (b) Exon  

 (c) Muton (d) Intron 

22 Net charge of DNA molecule is     

 (a) Positive (b) Negative 

 (c) Neutral  (d) none of these   

 

2: Totipotency and morphogenesis, nutritional requirements of in-vitro 

cultures 

23 Which of the following favors root induction in tissue culture?   

 (a) Equal auxin to cytokinin ratio (b) High auxin to cytokinin 

ratio 

 (c) Low auxin to cytokinin ratio (d) High cytokinin to auxin 

ratio 

24 The progeny regenerated from tissue cultured plantlets is denoted as..    

 (a) R0 (b) R1 

 (c) R3 (d) R2 

25 Agar is isolated from 

 (a) Bacteria  (b) Yeast 

 (c) Weed (d) Algae 

26 The most common carbon source used in plant tissue culture media 

is  

 (a) Fructose  (b) Sucrose  

 (c) Glucose  (d) Galactose  

27 Shoot proliferation from callus is promoted by   

 (a) IAA/NAA (b) BAP/BA 

 (c) GA3 (d) ABA 

 

28 Which of the following is a thermo labile compound 

 (a) Plant growth regulators  (b) Agar  

 (c) Charcoal  (d) Micronutrients  

29 Which of the following is not a plant tissue culture nutrient medium  

 (a) MS (b) Gamborg 

 (c) B5 (d) S9 

30 The unorganized mass of the cells known as 

 (a) Callus 

 

(b) Embryo 

 

 (c) Proliferation (d) Quotient cell 

31 The formation of an entire plant from cultured explants 

 (a) Callus (b) Regeneration 

 (c) Embryogenesis (d) Organogenesis 

32 Excised plant portion used to initiate plant tissue culture       

 (a) Callus  (b) Medium  

 (c) Explant  (d) Cybrid  

33 Regeneration of plant from tissue of actively dividing organ like stem 

tip 

 (a) Shoot culture 

 

(b) Meristem culture 

 

 (c) Organ culture (d) Cell culture 

34 The growth of tissue of living organism in suitable culture medium 

 (a) Cell culture 

 

(b) Organogenesis  

 

 (c) Morphogenesis (d) Tissue culture 

35 Commonly used gelling agent is 

 (a) Gelatine 

 

(b) Vermiculite 

 

 (c) Charcole (d) Agar 

36 Agarose powder isolated from   

 (a) Bacteria 

 

(b) Fungus 

 

 (c) Algae (d) Yeast 

37 The development of a structure from an unorganized state to 

differentiated and organized state    

 (a) Redifferentiation (b) Totipotency 

 (c) Morphogenesis (d) All of these  

38 For filter sterilization pore size should be …… 

 (a) < 0.45 µ (b) >0.45 µ 

 (c) >0.45 mm (d) >25mm 

39 For explants sterilization …….%Mercuric chloride concentration 

generally used 

 (a) 0.1-1.0% (b) 5-10 % 

 (c) 0.001-0.01% (d) 20-25% 

40 Which of the following chemicals not used for sterilization of explants  

 (a) Bromine water (b) H2O2 

 (c) HgCl2 (d) Si 

41 ……% ethanol used for sterilization of explants  

 (a) 10 (b) 20 

 (c) 50 (d) 70 

42 Nutrients required ……………concentration is known as 

macronutrients.   

 (a) >0.5m mol/l (b) >0.005 m mol/l 

 (c) <0.5m mol/l (d) <0.005m mol/l 

43 Nutrients required ……………in concentration is known as 

micronutrients.   

 (a) >0.5m mol/l (b) >0.005 m mol/l 

 (c) <0.5m mol/l (d) <0.005m mol/l 

     

3: Techniques of in-vitro cultures, micro propagation, anther culture, pollen 

culture, ovule culture, embryo culture, test tube fertilization, endosperm 

culture and factor affecting in-vitro culture. 

44 Polarity of somatic embryo is     

 (a) Multipolar (b) Monopolar 

 (c) Bipolar  (d) All of these  

45 Embryo rescue technique helps to overcome 

 (a) Post-fertilization barrier   (b) Vitrification  

 (c) Browning problem (d) Pre-fertilization barrier   

46 The formation of embryos from callus is known as   

 (a) Parthenogenetic (b) Indirect embryogenesis 

 (c) Direct embryogenesis  (d) None of these  

47 Seed propagation of sterile plant is possible through    

 (a) Pollen culture   (b) Ovary culture   

 (c) Invitro fertilization (d) Synthetic seed 

48 High sucrose level acts as _____ in pollen culture medium 

 (a) Diffusion (b) Plasmolytic 

 (c) Osmolytic (d) Osmoregulator 

49 Hyper hydration/vitrification problem is associated with   

 (a) Micropropagation  (b) Pollen culture  

 (c) Embryo culture  (d) Ovule culture  

50 The development of somatic embryo from other than Meristematic cell 

is describe as 

 (a) Androgenic embryo 

 

(b) Parthenogenetic embryo 

 

 (c) Gamatophytic embryo (d) Adventives embryo 

51 Induction phase of embryo genesis is promoted by   

 (a) Auxin 

 

(b) ABA 

 

 (c) Cytokinin (d) GA3 

52 For embryogenesis which of the following developmental events are in 

correct sequence 

 (a) Heart shapedGlobular 

shapetorpedo 

shapedcotyledonary stage 

(b) Globular shape  Heart 

shaped Torpedo 

shapedCotyledonary 

stage 

 (c) Globular shape  Torpedo 

shaped  Heart shaped 

Cotyledonary stage 

(d) Heart shaped torpedo 

shaped  Globular shape 

cotyledonary stage 

53 Gynogenesis term related to   

 (a) Fertilized ovule 

 

(b) Unfertilized ovule 

 

 (c) Mature ovule (d) Both A and B 

 

54 In which phase the rate of cell division is highest   

 (a) Lag phage 

 

(b) Linear phase 

 

 (c) Exponential phage (d) Stationary phase 

55 In which phase the rate of cell expansion is increase 

 (a) Declaration phase 

 

(b) Linear phase 

 

 (c) Exponential phage (d) Stationary phase 

56 In which phase the both rate of cell division and  expansion are 

decline 

 (a) Declaration phase 

 

(b) Linear phase 

 

 (c) Exponential phage (d) Stationary phase 

57 In pollen culture medium high sucrose level may act as 

 (a) Osmoregulatory 

 

(b) Plasmolytic 

 

 (c) Osmolytic (d) Diffusion 

58 The technique which used to recover hybrid from sexually 

incompatible species 

 (a) In vitro fertilization 

 

(b) In vitro pollination 

 

 (c) Embryo culture (d) Unfertilized ovule 

59 The ploidy level of primary endosperm cell is 

 (a) 2n 

 

(b) n 

 

 (c) 3n (d) 4n 

60 Pre-fertilization barrier in wide hybridization can be overcome by 

 (a) Embryo culture 

 

(b) Embryo rescue 

 

 (c) In vitro pollination (d) Anther culture 

61 Virus free plantlets can be produce through 

 (a) Stem cutting (b) Meristem culture  

 (c) Organ culture  (d) Microspore culture 

62 Browning in plant tissue culture media occurs due to      

 (a) Polyphenols  (b) Sugar 

 (c) Vitamins  (d) Charcoal  

63 The tendency of callus cells to separate easily is known as      

 (a) Friability  (b) Hybridity  

 (c) Callusing  (d) Granulation  

64 Regeneration of plant from tissue of actively dividing organ like stem 

tip 

 (a) Shoot culture 

 

(b) Meristem culture 

 (c) Organ culture (d) Cell culture 

65 The culture used for triploid production is 

 (a) Pollen (b) Endosperm 

 (c) Embryo (d) Ovary 

66 The production of haploid can be done by  

 (a) Chromosome elimination (b) Chromosome doubling 

 (c) Double fertilization  (d) All of these  

67 In which phase cell attain capacity for embryogenesis and develop up 

to globular stage 

 (a) Developmental 

 

(b) Induction 

 

 (c) Maturation (d) Germination 

68 The production of haploid embryo or plantlets from pollen grain is 

known as   

 (a)  Androgenesis 

 

(b) Androgenetic 

 

 (c) Gynogenesis (d) Both A and B 

 

 

69 Which of the following hormone used for maturation of somatic 

embryo 

 (a) ABA (b) NAA 

 (c) IBA (d) IAA 

70 Generally pH of media adjusted at …… 

 (a) 3.8 (b) 5.8 

 (c) 6.8 (d) 7.8 

 

4: Application and achievements of somaclonal variation, types and reasons 

71 When somaclonal variation is not heritable, it is called  

 (a) Epigenetic  (b) Genetic  

 (c) Calliclonal (d) Protoclonal 

72 Somaclonal variety of Indian mustard is 

 (a) Pusa Kiran (b) Pusa Bold 

 (c) Varuna (d) Pusa Jaikishan 

73 The basis of somaclonal variation is 

 (a) Karyotype change 

 

(b) Transposable element 

 

 (c) Gene mutation (d) All of these 

74 The variety developed by somaclonal variation in sugarcane for Fiji 

disease resistant is   

 (a) Pindar 

 

(b) Ono 

 

 (c) Bio 902 (d) Valvet 

75 The variety developed by somaclonal variation in Lytharus sativus for 

low neurotoxin (BOAA) is   

 (a) Pindar 

 

(b) Stephen 

 

 (c) Rattan (d) Valvet 

76 Mustard Variety Pusa Jaikishan of develop from Varuna through 

which techniques     

 (a) Somatic hybridization 

 

(b) Cybrid 

 

 (c) Gamatoclonal variation (d) Somaclonal variation 

77 Variability generated in tissue cultured plant is known as  

 (a) Somatic variation (b) Somaclonal variation 

 (c) Tissue variation (d) Germinal variation 

78 Variation observed among the callus culture is known as …  

 (a) Calliclonal variation (b) Gametoclonal variation 

 (c) Protoclonal variation (d) Androclonal variation 

79 Variation observed among anther (or) pollen culture is known as 

 (a) Protoclonal variation (b) Androclonal variation 

 (c) Androclonal variation (d) Calliclonal variation 

80 Variation observed among ovule (or) ovary culture is known as… 

 (a) Protoclonal variation (b) Gynoclonal variation: 

 (c) Androclonal variation (d) None of these 

81 Variation observed among protoplast culture is known as … 

 (a) Protoclonal variation (b) Gynoclonal variation: 

 (c) Androclonal variation (d) None of these 

 

5: Somatic embryogenesis and synthetic seed production technology 

82 Fertilized ovule culture will produce     

 (a) Haploid  (b) Diploid  

 (c) Triploid  (d) Pentaploid  

83 Synthetic seeds are encapsulated by the chemical  

 (a) Agar (b) Ca-Alginate  

 (c) Polypropylene   (d) Wax  

84 Encapsulation of somatic embryo is required in case of 

 (a) Somaclonal variation (b) Synthetic seed 

 (c) Pollen culture  (d) All of these 

85 The encapsulated somatic embryo is: 

 (a) Capsulation 

 

(b) Synthetic seed 

 

 (c) Somatic seed (d) All of above 

86 The concept of synthetic seeds was developed and term used by  

 (a) Toshiba Murashige (b) Smith 

 (c) Nathan (d) Maheswari et al 

87 Artificial seeds may be produced by following ways… 

 (a) Desiccated (b) Hydrated systems 

 (c) None of these (d) a & b both 

 

6: Protoplast isolation, culture, Manipulation and Fusion; Production of 

somatic hybrid and cybrids, their application in crop improvement 

88 Pomato is an example of 

 (a) Hybrid (b) Dybrid 

 (c) Vybrid (d) Cybrid 

89 Who used enzyme for protoplast isolation first time  

 (a) Takebe et al (b) Cocking et al 

 (c) White (d) Kranz et al 

90 The cell devoid of cell wall and nucleus is known as     

 (a) Cytoplast  (b) Protoplast  

 (c) Cytome (d) Chloroplast  

91 In case of protoplast fusion, which of the following stages are in correct 

sequence 

 (a) Agglutination  Membrane fusion Rounding off of protoplast   

 (b) Rounding off of protoplast  Membrane fusion  Agglutination 

 (c) Membrane fusionRounding off of protoplast  Agglutination 

 (d) Membrane fusion  Agglutination  Rounding off of protoplast   

92 Application of electric current for protoplast fusion is known as    

 (a) Microinjection (b) Electrophoresis  

 (c) Electroporation  (d) None of these 

 

 

93 Spontaneous fusion of protoplasts often produces 

 (a) Homokaryon (b) Heterokaryon  

 (c) Vybrid (d) Both (a) and (b)  

94 Pectinase enzyme isolated from 

 (a) Aspergillus niger 

 

(b) Rhizopus spp 

 

 (c) Trichoderma viride (d) Trichoderma harsianum 

95 Macerozyme isolated from 

 (a) Aspergillus niger 

 

(b) Rhizopus spp 

 

 (c) Trichoderma viride (d) Trichoderma harsianum 

96 The somatic hybrid with normal protoplast of one species and nucleus 

less protoplast of other species is called 

 (a) Somatic Hybrids 

 

(b) Cybrids 

 

 (c) Vybrids (d) Cytoplast 

97 The cellulose enzyme derived from   

 (a) Fungus 

 

(b) Yeast 

 

 (c) Algae (d) Bacteria 

98 Most Commonly used fusogen is   

 (a) Diethyl sulphonate 

 

(b) Sodium nitrate 

 

 (c) Poly Ethylne Glycole (d) Isozyme 

99 Which of the following are used as osmoticum    

 (a) Sorbitiol 

 

(b) Manitol 

 

 (c) Glucose (d) All of these 

100 The osmoticum added  in protoplast isolation for 

 (a) To prevent bursting of 

protoplast 

 

(b) Maintain osmotic 

pressure 

 

 (c) Increase osmosis (d) Reducing osmotic potential 

101 The hybrid is produced due to partial hybridization is    

 (a) Asymmetric hybrid 

 

(b) Symmetric hybrid 

 

 (c) Cybrid (d) Vybrid 

102 The novel interspecific hybrid-pomato is developed by      

 (a) Somatic hybridization 

 

(b) Somaclonal variation 

 

 (c) Transgenic breeding (d) Conventional breeding 

103 The hybrid which developed through fusion of two normal protoplast of 

different source 

 (a) Symmetric hybrid 

 

(b) Cybrid 

 

 (c) Asymmetric hybrid (d) Vybrid 

7: Genetic engineering, restriction enzyme and vector for gene transfer-gene 

cloning.  

104 The enzyme which is used for joining DNA fragment is called 

 (a) S1 Nuclease (b) Nuclease  

 (c) Ligase  (d) DNA polymerase  

105 Restriction endonucleases are also known as       

 (a) Molecular scissor  (b) Scalpel   

 (c) knives   (d) Cutter   

106 Restriction enzymes protect bacterial DNA by the process of …………..      

 (a) Methylation  (b) Super coiling 

 (c) Addition of OH group  (d) Acetylation   

 

107 The enzyme T4 ligase is generally obtained from   

 (a) Mycoplasma (b) Fungi  

 (c) Bacteriophage  (d) Bacteria 

108 The restriction endonucleases were discovered by 

 (a) Sharp and Robert  (b) Hedertberg and Meselon 

 (c) Smith and Nathans (d) Temin and Baltimore 

109 BamHI is belong to which category of Restriction enzyme 

 (a) Type-III (b) Type-I 

 (c) Type-II (d) Type-IV 

110 Restriction endonucleases having identical recognition sequence but 

different cleavage sites are called   

 (a) Schizomers (b) Isoschizomers 

 (c) Neomers (d) Neoschizomers 

111 Which of the following is DNA modifying enzyme ? 

 (a) S1 Nuclease (b) Cellulase 

 (c) Protease (d) RNAse  

112 DNA ligase joins two DNA molecules by formation of which bond 

 (a) Peptide (b) Disulphide 

 (c) Phosphodiester (d) Hydrogen bond 

113 Recognition sequence of HindIII is    

 (a) 5' GAATTC 3' 

3' CTTAAG5' 

(b) 5' AGCT 3' 

3' TCGA 5' 

 (c) 5' AAGCTT 3' 

3' TTCGAA 5' 

(d) 5' TCGA 3' 

3' AGCT 5' 

114 Widely used restriction endonuclease for gene cloning is?   

 (a) Type-III (b) Type-I 

 (c) Type-II (d) Type-IV 

115 Hind III is belong to which category of Restriction enzyme 

 (a) Type-III (b) Type-I 

 (c) Type-II (d) Type-IV 

116 EcoR1 is a ………… restriction enzyme   

 (a) Type-III (b) Type-I 

 (c) Type-II (d) Type-IV 

117 The enzyme which degrades nucleic acid is?    

 (a) Ligase    (b) Nucleases 

 (c) Kinase  (d) S1 Nuclease 

118 The enzyme used to synthesis of cDNA by using mRNA as template 

 (a) Transcriptase    (b) Reverse transcriptase 

 (c) DNA polymerase (d) RNA polymerase 

119 The complementary DNA obtained from RNA molecules is known as 

 (a) cDNA (b) tDNA 

 (c) rDNA (d) RNA 

120 The DNA is visualized after electrophoresis under U.V radiation due to  

 (a) Bromophenol blue (b) Tris HCL 

 (c) Chloromphenicol  (d) Ethidium bromide 

121 The enzyme reverse transcriptase was discovered by    

 (a) Temin and Baltimore (b) Maxam and Gilbert 

 (c) Smith and Nathan (d) Sharp and Robert 

 

122 The process of removal of non-coding sequence from mRNA is 

 (a) RNA editing (b) Capping 

 (c) Tailing (d) Splicing 

123 Which of the following dye is used as tracking dye during 

electrophoresis?    

 (a) Ethidium bromide (b) Tris HCL 

 (c) Chloromphenicol (d) Bromophenol blue 

124 The site recognized by restriction endonuclease are called  

 (a) Restriction sequence  

  

(b) Restriction sites 

 (c) Recognition sites (d) All of these 

125 The enzymes that cleaves or cut nucleic acid at internal sites.  

 (a) Endonuclease  (b) Exonuclease 

 (c) S1 nuclease (d) Exonuclease III 

126 Restriction endonuclease with  identical recognition and cleavage sites 

are called   

 (a) Schizomers  (b) Isoschizomers 

 (c) Neomers (d) Neoschizomers 

127 The molecule or segment produced by joining together two or more DNA 

segments from different organism is?  

 (a) rDNA  (b) rRNA 

 (c) cDNA (d) DNA 

128 Enzyme used for removal of RNA from DNA is known as …    

 (a) Ligase (b) Methylase 

 (c) Pectinase (d) RNAse 

129 Post transcriptional modification is known as…..  

 (a) RNA editing (b) Capping 

 (c) Tailing (d) Splicing 

130 Coding sequence of gene is 

 (a) Intron 

 

(b) Exon 

 (c) Muton (d) Recon 

131 The enzyme reverse transcriptase isolated from   

 (a) Mycoplasma (b) Bacteria 

 (c) Retroviruses (d) All of these 

132  1to 15 Kb size of DNA fragment can be accommodated in…..   

 (a) Phagemids (b) Plasmid 

 (c) BAC (d) YAC 

133 The organism which is used for cloning foreign DNA in bacteria is called   

 (a) Vector  (b) Small genome 

 (c) Chromosome (d) Viruses 

134 The vector used for production of the protein specified by the DNA insert 

is ? 

 (a) Shuttle vectors  (b) Cloning vectors 

 (c) Expressing vectors (d) None of these 

135 The number of plasmid present per bacterial cells is called  

 (a) Complementary number (b) Code number 

 (c) Copy number (d) Cose site number 

 

 

136 Vector having common characteristics of both Phage and plasmid is…..  

 (a) pUC 18 (b) YAC 

 (c) Phagemid  (d) pBR322 

137 The cloning capacity of BAC vector is……….. 

 (a) 150-300kb (b) 400kb 

 (c) 400-3000 kb (d) 400-1000 kb 

138 Which of the following is not a type of vector? 

 (a) Plasmid (b) Phagemid 

 (c) Cosmid (d) Transmid 

139 The most of the vectors used for transformation of DNA fragment in 

plant is based on 

 (a) Bacteriophages (b) YAC 

 (c) BAC (d) Ti plasmid 

140 The vector which have ability to replicate in cells of two different species 

or host 

 (a) Cosmid  (b) Phagemids 

 (c) Expressing vector (d) Shuttle vector 

141 Complementary molecules of DNA join to each other by ……..  ? 

 (a) Peptide  (b) Disulphate 

 (c) Phosphodiaster (d) Hydrogen bond 

142 The largest size of DNA fragment can be accommodate in   

 (a) Phagemids  (b) Plasmid 

 (c) Cosmids (d) YAC 

 

8: Direct and indirect method of gene transfer, transgenic plants and their 

application, and blotting techniques 

143 Agrobacterium is    

 (a) Plant bacterium   (b) Gram negative soil 

bacterium 

 (c) Gram positive soil bacterium (d) Both A and B 

144 Which of the following plasmid of Agrobacterium rhizogenes? 

 (a) Ti (b) Ri 

 (c) pBR322 (d) pUC 

145 Which of the following is not a direct transformation technique? 

 (a) Agrobacterium mediated (b) Microinjection  

 (c) Electroporation  (d) Microprojectile 

146 PEG is used in which of the following gene transfer methods?     

 (a) Microinjection (b) Biolistic   

 (c) Electroporation (d) Chemical mediated 

147 Which of the following gas is used in microprojectile method? 

 (a) Carbon dioxide (b) Helium 

 (c) Nitrogen (d) Oxygen 

148 Which part of the Agrobacterium is transferred in the host plant 

cells 

 (a) Vir region  (b) T-DNA 

 (c) Resistance gene region  (d) Opine gene region 

 

  

149 Gene gun method is also known as 

 (a) Electroporation  (b) Particle bombardment 

 (c) Agrobacterium mediated  (d) Microinjection  

150 Agrobacterium tumefacians  infected only dicot plant due to which 

chemical compounds   

 (a) Acetosyringone (b) Acetyle 

 (c) Acetogene (d) Syringone 

151 In fiber mediated transformation DNA is delivered into cell 

cytoplasm and nuclease by    

 (a) Fiber (b) Injection 

 (c) PEG (d) Silicon carbide fibers 

152 In particle bombardment method for delivering a foreign DNA into 

target plant cell by using   

 (a) Helium gas (b) Electric voltage 

 (c) PEG (d) Lipid vesicles 

153 DNA directly injected into the plant protoplast or cells using fine 

tipped glass needles    

 (a) Electroporation (b) Gene gun 

 (c) Micro injection (d) Electrophoresis 

154 Particle widely used in gene gun methods is made up by    

 (a) Gold (b) Silver 

 (c) Mercury (d) Iron 

155 Application of an electric current to cell for transforming DNA is?   

 (a) Electroporation (b) Gene gun 

 (c) Micro injection (d) Electrophoresis 

156 Introduction of DNA into cells via small lipids artificial vesicles is 

called   

 (a) Liposomes (b) Lypofection 

 (c) lysosomes (d) Both A and B 

157 The introduction or transfer of  DNA into the cells of an organism 

by a method other than sexual crossing   

 (a) Translation (b) Transformation 

 (c) Transduction (d) Both B and C 

158 Transgenic for male sterility-fertility mainly concerned with which 

genes? 

 (a) Cry-II (b) Cry-I 

 (c) Barnase and Barstar  (d) Cry-IAc 

159 The Cry-I protein are insecticidal to     

 (a) Lepidopteran  insect (b) Dipteran insect 

 (c) Coleopteran insect (d) Both A and B 

160 Flavr-Savr is a popular example of which transgenic crop? 

 (a) Potato  (b) Tomato 

 (c) Pomato (d) Brinjal 

161 Roundup ready is popular example of which transgenic crop? 

 (a) Cotton (b) Wheat 

 (c) Soybean (d) Both a and c 

162 Bollgard variety of cotton resistant against which insect- pest?  

 (a) Cotton bollworm (b) Tobacco bud worm 

 (c) Pink boll worm (d) All of these 

163 Round-up ready crop plant tolerant to which herbicide?  

 (a) Glyphosate (b) Pendemethalin 

 (c) 2-4-D  (d) Paraquat diquat 

164 Transgenic for male sterility-fertility mainly concerned with which 

genes? 

 (a) Barnase (b) Barstar 

 (c) Barnase and Barstar (d) None of these 

165 Golden rice accomplishes the requirement of which of the 

following? 

 (a) Vitamin B   (b) Vitamin A 

 (c) Vitamin A and D (d) Vitamin 12 

166 The second generation of transgenic plant is denoted by  

 (a) T0    (b) T2 

 (c) T1 (d) T3 

167 Flavr-Savr tomato having characteristics to    

 (a) Good test (b) Deep red colour 

 (c) Fast mature   (d) Delay ripening 

168 The barnase and barstar gene isolated from    

 (a) Bacillus amylolecufacians (b) B. thurengiensis 

 (c) Agrobacterium rhizogine   (d) Thermus equatics 

169 Bt gene isolated by 

 (a) Barton et al (b) Fodor 

 (c) Williams (d) Powell 

170 Bt gene isolated from 

 (a) Plant bacterium  (b) Soil bacterium 

 (c) Organism (d) Air spores 

171 The plant developed with a foreign gene is 

 (a) Transformed plant 

  

(b) Transplanted plant 

 (c) Transgenic plant (d) GMO 

172 The Cry-I protein are insecticidal to     

 (a) Lepidopteran  insect (b) Dipteran insect 

 (c) Coleopteran insect (d) Both A and B 

173 Golden rice is a good source of    

 (a) Vit-A (b) Amino acid 

 (c) Vit-B (d) Starch 

174 Which of the following cry protein can be used for protection 

against Lepidoptera insects ? 

 (a) CryI (b) Cry II 

 (c) Cry III (d) Both A and B 

175 Which of the following promoter is used for seed specific 

expression? 

 (a) 35S (b) TA29 

 (c) Adh1 (d) Vicilin 

176 Which of the promoter specific for anaerobic expression? 

 (a) Adh1 (b) TA29 

 (c) Vicilin (d) Crt1 

 

 

177 The first transgenic plant was produced in which of the following 

crop 

 (a) Tomato (b) Cotton  

 (c) Tobacco (d) Maize 

178 The first transgenic was produced which of the following character 

 (a) Ampicillin resistance (b) Neomycin  resistance 

 (c) Kanamycine resistance (d) Hygromycine resistance 

179 In which year first transgenic plant was developed   

 (a) 1973 (b) 1983 

 (c) 1993 (d) 2003 

180 In which of the following crop transgenic variety Flavr Savr was fist 

reach to market 

 (a) Tomato (b) Cotton  

 (c) Tobacco (d) Maize 

181 Which of the following blotting method is used for protein? 

 (a) Southern (b) Northern  

 (c) Western  (d) Eastern   

182 The technique used to separate DNA fragments is  

 (a) Southern blotting  (b) Gel electrophoresis 

 (c) SSR (d) PCR 

183 Transfer of nucleic acid fragment from gel to nitrocellulose or nylon 

membrane is known as     

 (a) Labelling (b) Probing 

 (c) Blotting (d) Hybridization 

184 A procedure in which RNA fragment are transferred from an 

agarose gel to nitrocellulose membranes or DBM membrane is 

known as … 

 (a) Northern blotting (b) Southern blotting 

 (c) Western blotting (d) Both A and B 

 

9: DNA finger printing, DNA based markers RFLP, AFLP, RAPD, SSR, and 

DNA probe 

185 Invitro amplification of DNA is done by 

 (a) Polymerase Chain Reaction (b) Polymerase Chain 

Reduction 

 (c) Gel documentation system (d) Gel electrophoresis  

186 Annealing step of  PCR involves  

 (a) Separation of two strands  (b) Rearrangement of DNA 

 (c) Joining of primer to 

complimentary strand  

(d) Super coiling 

187 Extension step  of PCR occurs at which temperature?    

 (a) 90 oC (b) 72 oC 

 (c) 60 oC (d) 94 oC 

188 Which of the following is not used for DNA finger printing 

 (a) RAPD (b) RFLP 

 (c) SSR (d) Blotting  

 

 

189 Short single stranded oligonucleotide that is used for DNA amplification 

in PCR is  

 (a) cDNA (b) Primer 

 (c) QTL (d) Probe 

190 The technique used to separate DNA fragments is  

 (a) Southern blotting  (b) Gel electrophoresis 

 (c) SSR (d) PCR 

191 Which of the following is not a PCR based marker? 

 (a) RAPD (b) RFLP 

 (c) SSR  (d) ISSR 

192 The fragment of DNA is separated by    

 (a) Chromatography (b) Electrophoresis 

 (c) Electroporation (d) PCR 

193 A small nucleotide sequence of DNA or RNA used to detect presence of 

complimentary sequence from nucleic acid sample    

 (a) Promoter (b) Regulatory sequence 

 (c) Marker (d) Probes 

194 The PCR techniques was developed by   

 (a) Kary Mullis (b) Smith and Nathan 

 (c) Craig ventor (d) Maxam and Gilbert 

195 The enzyme used in PCR is    

 (a) TaqDNA polymerase (b) DNA polymerase I 

 (c) DNA polymerase II (d) Reverse transcriptase 

196 TaqDNA polymerase isolated from   

 (a) B. amyloliquefaciens (b) Thermus aquatics 

 (c) B. tinctora (d) B. thermis 

197 Inheritance patterns of RAPD are? 

 (a) Dominant (b) Co dominant 

 (c) Non-expressing (d) Neutral 

198 The techniques of determining the order of bases of DNA molecules?    

 (a) DNA hybridization (b) DNA sequencing 

 (c) DNA ligation (d) DNA blotting 

199 Which of the following is co-dominant DNA markers?   

 (a) RFLP (b) RAPD 

 (c) SSR (d) Both a and c 

200 RFLP was the first molecular marker that was developed in ……. 

 (a) 1990 (b) 1880 

 (c) 1980 (d) 1890 

201 Which of the following is hybridization based marker? 

 (a) RFLP (b) AFLP 

 (c) RAPD (d) SSR 

202 Sequence information is not required for 

 (a) SSR (b) RAPD 

 (c) SNP (d) ESTs 

203 Single decamer primer used for which of the molecular marker 

 (a) RAPD (b) SSRs 

 (c) RFLP (d) ISSR 

 

 

204 RAPD marker annealed to the template DNA typically at ……… 

temperature.  

 (a) 37°C (b) 55°C 

 (c) 65°C (d) 72°C 

205 AFLP is a …..type of marker. 

 (a) Dominant  (b) Co-Dominant  

 (c) Partially co-dominant (d) None of these 

206 Polymorphism in SSR locus typically due to….  

 (a) Variation in repeat motif (b) Single nucleotide 

polymorphism 

 (c) Large insertion or deletion  (d) None of these 

207 For separation of RAPD marker  typically……..% gel is required   

 (a) 1% (b) 1.5% 

 (c) 3% (d) 5% 

208 RAPD marker was developed by  

 (a) Vos et al (b) Fodore 

 (c) Williams et al (d) None of these 

209 Which of the following marker is low reproducible 

 (a) SSR (b) RAPD 

 (c) SNP (d) AFLP 

210 Variation in SSR motif generated due to …. 

 (a) Replication slippage (b) Unequal recombination  

 (c) Transcription  (d) Both a & b 

211 Which of the following marker known as multi allelic marker 

 (a) SSRs (b) RAPD 

 (c) AFLP (d) ISSR 

212 Microsatellites are repeats of  

 (a) 1-6 bp (b) 5-10 bp 

 (c) 10-20 bp (d) 20-25 bp 

 

10: Mapping QTLs –Future prospects, MAS, and its application in crop 

improvement 

213 In 1975 the term QTL was coined by…… 

 (a) Smith (b) Gelderman 

 (c) Nathan (d) Khurana 

114 Region or locus on the chromosome associated with the expression of a 

quantitative trait is called as 

 (a) BIM (b) MCS 

 (c) Intron (d) QTLs 

215 Which of the following varieties is the first in India that were developed 

by Marker Assisted selection? 

 (a) Improved Pusa Basmati 1 

(Pusa 1460) 

(b) Sabarmati 

 (c) Pusa Basmati (d) IR64 

216 Which of the following character was transferred in Improved Pusa 

Basmati 1 through MAS?  

 (a) Heat tolerance (b) Bacterial Leaf Blight 

Resistance 

 (c) Cold tolerance (d) Insect Resistance 

217 Gene……………incorporated in Pusa Improved Basmati  

 (a) Xa21 (b) Xa 13 

 (c) Xa 1 (d) a and b both 

218 Which of the following is required for QTL mapping  

 (a) Mapping Population  (b) Polymorphic molecular 

marker 

 (c) Phenotypic data (d) All of these 

219 Which of the mapping population is immortal or permanent  

 (a) DH (b) F2 

 (c) RILs (d) a & c both 

220 In which of the mapping population heterosis effect of locus can be 

observed 

 (a) F2 (b) NILs 

 (c) RILs (d) DH 

221 Which of the following is utilized as mapping population?    

 (a) Backcross Line (b) Recombinant Inbred Line 

 (c) Double Haploid  (d) All of these  

222 Which of the following method used for QTLs identification? 

 (a) Single marker approach (b) Composite interval 

mapping 

 (c) Simple interval mapping (d) All of these 

223 Software package used for QTL detection  

 (a) QTL cartographer (b) Bioedit 

 (c) Nextgen (d) Mega 4.2 

224 Distance of markers in linkage map is defined by unit of  

 (a) cM (b) kM 

 (c) gM (d) pM 

225 Software package used for construction of linkage map 

 (a) MAPMAKER (b) Bioedit 

 (c) GMAP (d) Mega 4.2 

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