GPB(502) Principles of Cytogenetics (Question Paper)

Time: 2 hours
Max. Marks: 30

Final Theory Exam

Q. I. Define / Answer briefly

1. Environmental considerations

2. Environmental inversions

3. Complex inversions

4. Pseudo-dominance

5. Chromosomal Deletions

Q. II. Differentiate between

1. Alternate disjunction and Adjacent disjunction

2. Autopolyploids and Allopolyploids

Q. III. Answer the followings

1. Explain the morphological effects of polyploidy

2. Explain alternate disjunction with suitable diagram

3. Explain double reduction

4. Explain how genome analysis helps to identify probable progenitors of allopolyploids

5. List mechanisms of crossing over and explain the theory which is being widely accepted

6. Explain Alternate disjunction with suitable diagram

Q. IV. Fill in the blanks

1. Chromosomal deletions leads to genetic effect known as _____________.

2. Chromosomes forms "L" shape during Anaphase ________________.

3. Random pattern of inactivation of either maternal or paternal X-chromosomes linked to fur color in mice is known as _____________.

4. The process of ________________ leads to formation of polytene chromosomes.

5. The unique and characteristic _________is formed to facilitate chromosome pairing in inversion ________________.

6. The amount of DNA found in haploid genome represents ____________ and measured in _____________.

7. ________________ inversions leads to karyotype changes.

8. In external inter-chromosomal translocations, the chromosome segment is trans-located into a _____________________.