GPB (601) Principles of Genetics (Question Paper )

 

  

I. Answer the following in Brief (Any Five) (2.5 x 5 = 12.50 Marks)

1. What are multiple alleles? Explain with an appropriate example.
2. Describe the experiment of Meselson and Stahl (1958) with a diagram to prove that replication of DNA is semi-conservative.
3. Give the relationship between:
   (a) Crossing over and chiasma frequency
   (b) Interference and coefficient of coincidence.
4. List the different mechanisms of sex determination & explain how a single gene is able to determine sex in plants with an appropriate example.
5. Explain in brief the different methods of detection and estimation of linkage.
6. Explain different degrees of dominance with an appropriate example.

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II. Write the differences between the following (1 x 5 = 5.0 Marks)

1. Complete linkage & Independent assortment
2. Sex-limited traits & Sex-influenced traits
3. Three-point test cross & Two-point test cross
4. DNA Polymerase I & DNA Polymerase III
5. Qualitative & Quantitative traits

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III. Give one significant contribution of the following (0.5 x 5 = 2.5 Marks)

1. Bridges
2. Landsteiner & Weiner
3. Sturtevant & Plunkett
4. Lederberg & Tatum
5. Bateson & Punnett