GPB - 502 (2+1) Principles of Cytogenetics

Marks : 30

Q. I. Define / Answer briefly (1 x 5 = 05.00)

1. Robertsonian translocations

2. Nullisomic

3. Interstitial region

4. Pseudo-dominance

5. Displaced duplications

Q. II. Differentiate between (2.5 x 2 = 05.00)

1. Peri-centric and para-centric inversion

2. Intra-chromosomal and inter-chromosomal translocations

Q. III. Answer the followings (Any Four) (2.5 x 4 = 10.00)

1. Explain double reduction

2. Explain different types of trisomics

3. Explain alternate disjunction with suitable diagram

4. Explain breeding behavior of monosomics with suitable example

5. Explain the correlation between Mendel's principles with cytological events during cell division

Q. IV. Fill in the blanks (0.5 x 10 = 5.00)

1. The rate of achieving homozygosity is low in polyploids than their diploid counterparts

2. Ramage (1965) developed hybrid seed production techniques using Balanced fertility system in Barley

3. Loop formation in lampbrush chromosomes represents high rate of transcription

4. Supernumerary chromosomes follow Non-Mendelian inheritance due to lack of homologous pairing

5. Acesomes are maintained in linear order in Neurospora crassa

6. The loss of terminal segment of chromosomes is termed as Terminal deletion

7. Classical allopolyploids involves combination of very dissimilar genomes

8. Metacentric chromosomes form 'V' shape during Anaphase

Q. V. Match the Scientists name with their discoveries/contributions (10 x 0.5 = 5.00)

Block A	Block B
1. Restriction Enzyme	1. 2n-2
2. Secondary trisomics	2. 2n-1
3. Colchicine	3. Polyploids
4. Nitrous Oxide	4. EcoRI
5. Trisomic	5. Double haploids
6. Polypoids	6. 2n+2
7. Plasmids	7. 2n+1
8. Double monosomic	8. Haploids
9. Tetrasomic	9. Multiple cutting sites
10. Nullisomic	10. 2x+1L.1L
	11. ‘Gigas’ effect
	12. hap in Barley

best of luck