MCQ’s Based on Transformation and Recombination for ICAR (SRF or JRF) /ASRB /CSIR NET/BET Exams #1

 

1. Who introduced the term Nucleic Acid?
   A) Meisher
   B) Robert Brown
   C) Altmann
   D) Lipmann
   Ans: C

2. Which ratio is constant for DNA?
   A) A+G / T+C
   B) A+T / G+C
   C) A+C / U+G
   D) A+U / C+G
   Ans: B

3. If 30% of organism DNA is thymine, then
   A) 70% guanine
   B) 20% guanine
   C) 30% adenine
   D) both B & C
   Ans: D

4. If, in Griffith's experiment, a mixture of heat-killed smooth bacteria and living rough bacteria were injected into a mouse, it would be expected to
   A) kill the mouse
   B) cause transfection
   C) cause transduction
   D) have no effect on it
   Ans: A

5. RNA is sometimes the genetic material in
   A) Yeast
   B) Animals
   C) Bacteria
   D) Viruses
   Ans: D

6. If Hershey and Chase found only ³⁵S in the bacterial cells, they would conclude that
   A) Protein is the genetic material
   B) DNA and protein together serve as the genetic material
   C) DNA is the genetic material
   D) No conclusion is possible
   Ans: A

7. Techniques used to identify the location of genes on a chromosome include
   A) FISH
   B) Reassociation kinetics
   C) Repetitive DNA studies
   D) X-ray Crystallography
   Ans: A

8. Recombination in bacteria differs from recombination in eukaryotes in which of the following ways?
   A) A portion of DNA from one genome is replaced with homologous DNA from another strain of bacteria.
   B) Only the plasmid DNA goes through recombination in prokaryotes.
   C) Recombination does not occur in prokaryotes.
   D) Sister chromatids, instead of homologous chromosomes, exchange information during recombination.
   Ans: A

9. Which of these describes a Holliday junction?
   A) A section of DNA where base pairing is not exact.
   B) A strand of DNA containing genetic material from two different chromosomes.
   C) An interaction of two strands of DNA from homologous chromosomes.
   D) A three stranded DNA structure where single stranded DNA has invaded a double helix.
   Ans: C

10. After isomerization and resolution, the resulting chromosomes are
    A) Unchanged from the original chromosome.
    B) Nonrecombinant chromosomes with a heteroduplex region.
    C) Recombinant chromosomes with a heteroduplex region.
    D) Recombinant chromosomes without a heteroduplex region.
    Ans: D

11. Which statement regarding recombination is false?
    A) Recombination creates new combinations of alleles on a chromosome.
    B) Recombination commonly occurs between homologous sequences.
    C) Sister chromatid exchange is a form of recombination.
    D) Gene conversion may occur during recombination.
    Ans: C

12. Recombination of virus genomes occurs
    A) by transduction
    B) by transcription
    C) simultaneous infection of a host cell by two viruses with homologous chromosomes
    D) by transformation
    Ans: C

13. The type of recombination that commonly occurs between a pair of homologous DNA sequences is
    A) Mutagenic recombination
    B) Site-specific recombination
    C) Replicative recombination
    D) General recombination
    Ans: D