|
Aspect |
Genomic Selection (GS) |
Genome-Wide Association Studies
(GWAS) |
|
Objective |
Predicting breeding values for
selection purposes |
Identifying genetic variants
associated with traits |
|
Scope |
Predicts breeding values based on
genome-wide marker data |
Identifies marker-trait associations
across the genome |
|
Marker Use |
Utilizes genome-wide marker data for
prediction |
Utilizes marker-trait associations
for association mapping |
|
Sample Size |
Requires training population with
phenotypic and genotypic data for model calibration |
Requires large sample sizes for
detecting significant associations |
|
Target Trait |
Suitable for traits with moderate to
high heritability |
Suitable for traits influenced by
common genetic variants with moderate to large effects |
|
Precision |
Offers high predictive accuracy for
traits under selection |
Provides information on specific
genetic variants associated with traits |
|
Predictive Power |
Predicts the genetic merit of
individuals for breeding purposes |
Identifies genetic variants
contributing to phenotypic variation |
|
Application |
Widely used in plant and animal
breeding programs for genomic selection |
Commonly used in genetic studies to
dissect the genetic architecture of traits |
|
Validation Requirements |
Requires validation in independent
populations to assess prediction accuracy |
Typically requires replication of
significant associations in independent populations |
|
Genetic Architecture |
Suitable for traits influenced by
many small-effect loci |
Suitable for traits influenced by a
few large-effect loci or many small-effect loci |
|
Breeding Value Prediction |
Predicts the aggregate genetic value
of individuals based on marker data |
Estimates the effect size and
significance of individual markers on trait variation |
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