1. Which of the following event occur during metaphase of meiosis-I? 

A. Chiasma terminalization 

B. Arrangement of bivalents at equatorial plate 

C. Crossing over 

D. Separation of homologous chromosomes 


2. Chromosomes are clearly visible at: 

A. Metaphase 

B. Telophase 

C. Anaphase 

D. Prophase 


3. Crossing over takes place between: 

A. Homologous chromosomes 

B. Non homologous chromosomes 

C. Isochromosomes 

D. All of these 


4. One cycle of mitosis gives rise to: 

A. Two haploid cells 

B. Two diploid cells 

C. Four haploid cells 

D. Four diploid cells 


5. Shape of chromosome is determined by the position of 

A. Centromere 

B. Chromomere 

C. Telomere 

D. All of these 


6. In meiosis, Prophase-I is divided into _____sub-stages? 

A. Three 

B. Five 

C. Six 

D. Two 


7. Pairing of homologous chromosomes occur during which stage? 

A. Leptotene 

B. Pachytene 

C. Zygotene 

D. Diplotene 

 

8. Which of the following does not contain DNA? 

A. Golgi body 

B. Mitochondria 

C. Chloroplasts 

D. Nucleus 


9. Which of the following is the main function of chloroplasts? 

A. Protein synthesis 

B. Respiration 

C. Photosynthesis 

D. Glycolysis 


10. Packaging of food material is associated with 

A. Chloroplasts 

B. Golgi bodies 

C. Ribosomes 

D. Lysosomes 


11. Basic chromosome number is denoted by 

A. x 

B. n 

C. 2n 

D. 2n 


12. Which of the following can cause pseudo-dominance? 

A. Deletion 

B. Duplication 

C. Translocation 

D. Inversion 


13. Nulli-somics are represented by which of the following? 

A. 2n - 2 

B. 2n - 1 - 1 

C. 2n - 1 + 1 

D. 2n + 2 


14. How many somatic chromosomes are present in maize? 

A. 10 

B. 20 

C. 30 

D. 40 


15. Colchicine is extracted from which of the following? 

A. Colchicum autumnale 

B. Allium cepa 

C. Rosa indica 

D. Coleus blumei 


16. Tetra-somics are represented by which of the following? 

A. 2n + 2 

B. 2n - 1 - 1 

C. 2n - 1 + 1 

D. 2n + 2 


17. Inversion leads to change in 

A. Gene sequence 

B. Gene number 

C. Gene composition 

D. None of the above 


18. The genetic constitution of Brassica nigra is 

A. BB 

B. AABB 

C. AACC 

D. CC 


19. Which of the following is tetraploid species of Brassica 

A. B. campestris 

B. B. oleracea 

C. B. juncea 

D. B. nigra 


20. How many somatic chromosomes are present in Pearlmillet? 

A. 10 

B. 14 

C. 20 

D. 24 


21. Two ends of chromosomes are known as 

A. Telomere 

B. Holomere 

C. Chromomere 

D. Centromere 


22. Normally crossing over promotes 

A. Recombination 

B. Parental types 

C. Linkage 

D. All of these 


23. Frequency of crossing over never exceeds from 

A. 5 

B. 50 

C. 25 

D. 35 


24. Linkage can be determined by 

A. Test cross method 

B. Repeated inter mating 

C. Top cross method 

D. Back cross method 


25. Mendel discovered laws of inheritance working with 

A. Drosophila 

B. Garden pea 

C. Barley 

D. Maize 


26. How many characters did Mendel study in garden pea? 

A. 7 

B. 10 

C. 12 

D. 14 


27. When centromere is involved in the inversion, it is known as_____ inversion 

A. Metacentric 

B. Pericentric 

C. Peracentric 

D. Telocentric 


28. The change in chromosome number which involve entire set is called 

A. Anueploidy 

B. Polyploidy 

C. Euploidy 

D. None of the above 


29. In 1905, coupling and repulsion phase of linkage were given by 

A. Morgan 

B. Bateson and Punnet 

C. Muller 

D. Bridges 


30. A cross in which the order of male and female parents is reversed is called 

A. Back cross 

B. Test cross 

C. Reciprocal cross 

D. Direct cross 


31. Trihybrid ratio is 

A. 27:9:3:9:3:9:3:1 

B. 27:9:9:9:3:3:3:1 

C. 9:3:3:1 

D. 3:1 


32. The gene whose effect is masked is called 

A. Hypostatic gene 

B. Pleiotropic gene 

C. Modifier gene 

D. None of these 


33. Ratio of Duplicate dominant gene interaction is 

A. 9:3:4 

B. 15:1 

C. 12:3:1 

D. 9:3:3:1 


34. Ratio of Inhibitory epistasis is 

A. 13:3 

B. 15:1 

C. 12:3:1 

D. 9:7 


35.……… hydrogen bonds join adenine and thymine in a DNA molecule 

A. Single 

B. Double 

C. Triple 

D. All of these 


36. DNA is a polymer of 

A. Amino acids 

B. Nucleotides 

C. Proteins 

D. All of these 


37. How many codons are there in a genetic code? 

A. 64 

B. 4 

C. 16 

D. 32 


38. Who won Nobel prize for operon hypothesis 

A. Jacob and Monod 

B. Temin 

C. Baltimore 

D. Britten 


39. Mendel’ paper was published in 

A. Brunn society of plant hybridization 

B. Brunn society of plant history 

C. Natural history society of plant evolution 

D. Natural history society of Brunn 


40. In a DNA molecule, replacement of pyrimidine by pyrimidine is called 

A. Transfection 

B. Transversion 

C. Reversion 

D. Transition 


41. ‘P’   site, ‘A’   site   and ‘E’   site are associated with 

A. Protein synthesis 

B. t-RNA synthesis 

C. m-RNA synthesis 

D. DNA synthesis 


42. Who induced artificial mutation in plant by X-rays? 

A. Muller 

B. Stadler 

C. Seth Wright 

D. Mendel 


43. The mutation that show more than 50% mortality in the individuals that carry it:  

A. Lethal 

B. Sub-lethal 

C. Sub-Vital 

D. Sub-vital 


44. EMS stands for 

A. Ethylmethane sulphonate 

B. Ethylmethyl sulphonate 

C. Ethylmethane sulpher 

D. Ethyl Mustard sulphonate 


45. Quantitative character is also called 

A. Minor gene character 

B. Polygenic character 

C. Variable character 

D. All of these 


46. Kernel colour in wheat is a quantitative character and was studied by 

A. Nilsson-Ehle 

B. Mendel 

C. Morgan 

D. Muller 


47. ABO blood group in human is the example of which of the following? 

A. Complete dominance 

B. Incomplete dominance 

C. Co-dominance 

D. Both b) and c) 

 


48. Within a gene, a unit of mutation is called 

A. Hot spot 

B. Cistron 

C. Muton 

D. Recon 


49. The sections of DNA (or RNA) that code for proteins are called 

A. Introns 

B. Exons 

C. Sensor sequence 

D. None of the above 


50. Non-coding section of the RNA transcript is 

A. Introns 

B. Exons 

C. Sensor sequence 

D. None of the above 


51. Tendency of two or more genes to stay together during inheritance is known as 

A. Crossing over 

B. Interference 

C. Recombination  

D. Linkage 


52. The characters for which genes are present in Y chromosome are known as 

A. Sex linked character 

B. Sex influenced character 

C. Female character 

D. Holandric character 


53. Linkage between dominant or recessive alleles of two or more genes is known as 

A. Coupling phase 

B. Repulsion phase 

C. Repulsive phase 

D. Compulsive phase 


54. Tendency of one crossing over to reduce the chance of another crossing over in the adjacent 

region is known as 

A. Coincidence 

B. Interference 

C. Dosage compensation 

D. None of the above 


55. Mutual exchange of chromosomal segments between non homologous chromosomes is 

known as 

A. Translocation 

B. Crossing over 

C. Shift 

D. Reciprocal translocation 


56. Expression of recessive allele in the absence of its dominant allele is known as 

A. Incomplete dominance  

B. Pseudo dominance 

C. Co dominance 

D. Complete dominance 


57. Largest unit of a gene  

A. Cistron  

B. Recon  

C. Muton 

D. Both A) and C) 


58. Most abundant type of RNA is 

A. rRNA 

B. tRNA 

C. mRNA 

D. None of the above 


59. Lack of chlorophyll in green plant and of melanin from skin is known as 

A. Albinism 

B. Discoloration 

C. Chlorosis 

D. All of the above 


60. One gene one enzyme hypothesis was proposed by  

A. Beadle and Tatum  

B. Watson and Crick 

C. Jacob and Monod 

D. None of the above 


61. Production of complementary DNA copy from mRNA is termed as 

A. Transcription  

B. Translation 

C. Tenalism 

D. None of the above 


62. Negative interference has been observed in 

A. Blue green Algae 

B. Grasshopper 

C. Bacteriophages 

D. None of the above 


63. Which of the following is not a part of nucleosome core 

A. H2a 

B. H2b 

C. H1 

D. H3 


64. Loop of lampbrush chromosome are the sites of 

A. RNA synthesis  

B. DNA synthesis 

C. Ribosome synthesis 

D. DNA replication 


65. First AICRP started in the year, 1957 with the collaboration of  

A. ICRISAT 

B. Bill and Melinda gates foundation 

C. Both A) and B) 

D. Rockefellar and Ford foundation  


66. Pulses are deficient in  

A. Tryptophan 

B. Methionine 

C. Both A) and B) 

D. None of the above 


67. The plasmid that carry genes for resistance to antibiotics 

A. R plasmid  

B. Col plasmid  

C. F plasmid 

D. All of the above 


68. A map unit or centimorgan is that distance, which allows  

A. 10% recombination  

B. 1% recombination 

C. 20% recombination  

D. 100% recombination 


69. The human Genome Project was officially began on  

A. October 1, 1990 

B. October 1, 1991 

C. September 1, 1990 

D. September 1, 1991 


70. Which of the following is a hybrid marker 

A. RFLP  

B. RAPD 

C. AFLP 

D. Both A) and C 


71. Minisatellite DNAs are usually 

A. 200-2000bp 

B. 0.2-2bp 

C. 20-200bp 

D. None of the above  


72. In southern hybridization……….is separated by gel electrophoresis 

A. DNA 

B. RNA 

C. Protein 

D. Both A) and C) 


73. Library of expressed genes is  

A. Universal library 

B. Library of California University 

C. cDNA library 

D. Genomic Library 


74. Pollymerase Chain Reaction was developed by 

A. Kary Mullis 

B. W. Arber 

C. Smith  

D. Both A) and C)  


75. What is not right about to central dogma 

A. Genetic information transferred from nucleic acid to nucleic acid 

B. Genetic information transferred from RNA to Protein 

C. Both A) and B) 

D. Genetic information transferred from Protein to nucleic acid 


76. The -10 sequence of transcription unit is also known as  

A. TATA box 

B. Pribnow box 

C. Both A) and B) 

D. None of the above 


77. RNA polymerase I is occurs in  

A. Ribosome 

B. Nucleoplasm 

C. Nucleolus 

D. Both A) and C) 


78. Target genes for RNA polymerase II are 

A. rRNA genes 

B. mRNA genes 

C. Both A) and B)  

D. tRNA genes 


79. Puff are found in 

A. Lampbrush chromosome    

B. Polytene chromosome 

C. Isochromosome                                            

D. B chromosome 


80.  Loop are found in  

A. Lampbrush chromosome      

B. Polytene chromosome  

C. Isochromosome       

D. B chromosome 


81. In prokaryotes mostly 

A. Negative mechanism of gene regulation is found 

B. Positive mechanism of gene regulation is found 

C. Both A) and B) 

D. None of the above 

 

82. The first transgenic plant against virus disease is produced in 

A. Tomato 

B. Soybean 

C. Brinjal 

D. Tobacco 

 

83. Dimethyl Sulphoxide (DMSO) is a  

A. Anti-transpirant 

B. Cryoprotactant 

C. Fusogen 

D. All of the above 

 

84. Gene for gene concept was given by  

A. Flor 

B. K.C. Mehta 

C. Vanderplank 

D. None of the above 

 

85. Tift 23A and Tift 23D2A are male sterile lines of 

A. Sorghum 

B. Pearlmillet 

C. Maize 

D. Cotton 

 

86. Oligogenic resistance is synonymous to 

A. Horizontal resistance 

B. Vertical resistance 

C. Both A) and B) 

D. None of the above 

 

87. Monogenic resistance is………durable than polygenic resistance 

A. More 

B. Less 

C. Highly 

D. All of the above 

 

88. Frame shift mutation produced due to 

A. Base substitution 

B. Base addition  

C. Base deletion 

D. Both B) and C) 

 

89. Which of the following is a start codon? 

A. UAA 

B. UAG 

C. AUG 

D. UGA


90. Prabhavati is a mutant variety of  

A. Wheat 

B. Rice 

C. Maize  

D. Sorghum 

 

91. H4 first cotton hybrid is a 

A. Inter varietal hybrid 

B. Inter specific hybrid 

C. Intergeneric hybrid 

D. None of the above 

 

92. DSH-129 is a hybrid variety of  

A. Sunflower 

B. Safflower 

C. Sorghum 

D. Sugarcane 

 

93. Dominance hypothesis of heterosis was proposed by 

A. Davenport 

B. Bruce, Keeble and Pellew 

C. Shull 

D. All of the above 

 

94. RNA as the genetic material was first reported by  

A. Griffing 

B. Avery Macleod and McCarty 

C. Frankel Conrat and Singer 

D. None of the above  

 

95. Which form of DNA is common in vivo? 

A. A-DNA 

B. B-DNA 

C. C-DNA 

D. Z-DNA 

 

96. Dehydrated DNA occurs in the 

A. A form 

B. B form 

C. Z form 

D. None of the above 

 

97. The size of pBR 322 is  

A. 4363bp 

B. 5000bp 

C. 3580bp 

D. 2700bp 

 

98. DNA replication always proceeds in 

A. 5’-3’ direction 

B. 3’-5’ direction 

C. Both A) and B) 

D. None of the above 

 

99. DNA replication is always 

A. Unidirectional 

B. Bidirectional  

C. Both A) and B) 

D. None of the above 

 

100. Rolling circle model of DNA replication occurs in  

A. Phi-phage174 

B. Mammals 

C. Adenovirus 

D. All of the above